翻訳と辞書 Words near each other ・ RNF216 ・ RNF220 ・ RNF24 ・ RNF25 ・ RNA Automation ・ RNA binding motif protein, Y-linked, family 1, member A1 ・ RNA Biology ・ RNA biology ・ RNA CoSSMos ・ RNA editing ・ RNA extraction ・ RNA Framework ・ RNA helicase ・ RNA Helicase A ・ RNA helicase database ・ RNA hydrolysis ・ RNA integrity number ・ RNA interference ・ RNA journal ・ RNA ligase (ATP) ・ RNA modification ・ RNA modification database ・ RNA of unknown function ・ RNA polymerase ・ RNA polymerase I ・ RNA polymerase II ・ RNA polymerase II holoenzyme ・ RNA polymerase II subunit B4 ・ RNA polymerase III ・ RNA polymerase IV Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RNA hydrolysis ： ウィキペディア英語版 RNA hydrolysis RNA hydrolysis is a reaction in which a phosphodiester bond in the sugar-phosphate backbone of RNA is broken, cleaving the RNA molecule. RNA is susceptible to this base-catalyzed hydrolysis because the ribose sugar in RNA has a hydroxyl group at the 2’ position.〔 This feature makes RNA chemically unstable compared to DNA, which does not have this 2’ OH group and thus is not susceptible to base-catalyzed hydrolysis. ==Mechanism== RNA hydrolysis occurs when the deprotanated 2’ OH of the ribose, acting as a nucleophile, attacks the adjacent phosphorus in the phosphodiester bond of the sugar-phosphate backbone of the RNA.〔 There is a transition state (shown above), where the phosphorus is bonded to five oxygen atoms.〔 The phosphorus then detaches from the oxygen connecting it to the adjacent sugar, resulting in ester cleavage of the RNA backbone. (This mechanism is also referred to as RNA cleavage.) This produces a 2’,3’-cyclic phosphate that can then yield either a 2’- or a 3’-nucleotide when hydrolyzed. This process is shown in Figure 1.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RNA hydrolysis」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.